张松柏

教授

硕士生导师

Email: zsb0119@163.com

个人简历

张松柏，1982年生，男，理学博士，教授，硕士生导师，湖南省121创新人才工程人选，湖南省普通高校青年骨干教师，湖南省化学化工学会常务理事，涂料化工校企合作创新创业教育基地负责人，水处理功能材料省重点实验室副主任，电镀废水回用技术省工程研究中心副主任。历任化学与材料工程学院科研秘书、化学教研室主任、副院长、副书记。湖南大学化学生物传感与计量学国家重点实验室分析化学专业获博士学位（2004.09-2009.06），中南大学化学博士后（2015.04-2017.04），美国伊利诺伊大学香槟分校访问学者（2017.09-2018.09）。主要从事无机纳米材料与核酸纳米材料的制备与应用、生化分析新方法、传感器构建新技术以及细胞成像和靶向递药等领域的研究，主持国家自然科学基金、中国博士后科学基金、湖南省自然科学基金等项目10余项，企业横向项目5项，发表SCI论文60余篇，授权发明专利1项，出版专著1部，获湖南省教学成果二等奖1项，湖南省自然科学三等奖2项。

研究方向

1.      功能纳米材料制备与应用

2.      生物传感与生化分析技术

3.      细胞成像与靶向递药研究

代表性论著

1.          Zhaohong Su, Jiaqi Wang, Shiyu Hu, Yongbing Cheng, Yuan Yang, Shumo Zhou, Min Chen, Qinyi Cao, Songbai Zhang*, Lixia Yang, Zhonghua Liu*, Xinman Tu*.   In-situ reshaping nano-biochar on electrode surface for machine learning   assisted selective sensing of Pb²⁺ in real water samples. Applied   Surface Science, 2024: 160294.

2.          Jing Yang, Changxi Deng,   Wei Zhong, Guanwei Peng, Jin Zou, Yan Lu, Yansha Gao*, Mingfang Li, Songbai   Zhang*, Limin Lu*.   Electrochemical activation of oxygen vacancy‑rich   TiO₂@MXene as high‑performance electrochemical sensing platform for   detecting imidacloprid in fruits and vegetables. Microchimica Acta, 2023,   190:146.

3.          Zhenmeng Wang, Jinrui Lv,   Hong Huang, Huo Xu, Jingjing Zhang, Chang Xue*, Songbai   Zhang*, Zai-Sheng Wu*.   Structure-switchable aptamer-arranged reconfigurable DNA nanonetworks for   targeted cancer therapy. Nanomedicine: Nanotechnology, Biology, and Medicine,   2022, 43: 102553.

4.          Yansha Gao^#, Songbai   Zhang^#, Chengwei Wu,   Qian Li, Zhifa Shen, Yi Lu*, Zai-Sheng Wu*. Self-protected DNAzyme walker   with a circular bulging DNA shield for amplified imaging of miRNAs in living   cells and mice. ACS Nano, 2021, 15: 19211-19224.

5.          Songbai Zhang, Yunxia Luan*, Mengyi Xiong, Jingjing Zhang, Ryan Lake,   Yi Lu*. DNAzyme amplified aptasensing platform for ochratoxin A detection   using a personal glucose meter. ACS Applied Materials Interfaces, 2021, 13:   9472-9481.

6.          Chang Xue^#, Songbai   Zhang^#, Xin Yu, Shuyao   Hu, Yi Lu*, Zai-Sheng Wu*. Periodically ordered, nuclease-resistant DNA   nanowires decorated with cell-specific aptamers as selective theranostic   agents. Angewandte Chemie-International   Edition, 2020, 59: 17540-17547.

7.          Changhe Ouyang^#,   Songbai Zhang^#, Chang Xue^#, Xin Yu, Huo Xu, Zhenmeng Wang,   Yi Lu*, Zai-Sheng Wu*. Precision-guided missile-like DNA nanostructure   containing warhead and guidance control for aptamer-based targeted drug   delivery into cancer cells in vitro and in vivo. Journal of the American   Chemical Society, 2020, 142(3): 1265-1277.

8.          Chang Xue^#, Songbai   Zhang^#, Congcong Li, Xin   Yu, Changhe Ouyang, Yi Lu*, Zai-Sheng Wu*. Y-Shaped Backbone-Rigidified   Triangular DNA Scaffold-Directed Stepwise Movement of a DNAzyme Walker for   Sensitive MicroRNA Imaging within Living Cells. Analytical Chemistry, 2019, 91(24):   15678-15685.

9.          Zhe Yang^#, Songbai   Zhang^#, Hui Zhao, Huimin   Niu, Zai-Sheng Wu*, Huan-Tsung Chang. Branced DNA junction-enhanced   isothermal circular strand displacement polymerization for intracellular   imaging of microRNAs. Analytical Chemistry, 2018, 90: 13891-13899.

10.      Jifeng Yang, Min He,   Tengfei Wu, Aiping Hao, Songbai Zhang*, Yuandao Chen, Shibiao Zhou, Liying Zhen, Rong Wang,   Zilin Yuan, Lin Deng*. Sulfadiazine oxidation by permanganate: Kinetics,   mechanistic investigation and toxicity evaluation. Chemical Engineering   Journal, 2018, 349: 56-65.

11.    Songbai Zhang*, Xia Hu, Xiaohui Yang,   Qinli Sun, Xiaolin Xu, Xuewen Liu, Guangyu Shen, Jilin Lu, Guoli Shen and   Ruqin Yu. Background eliminated signal-on electrochemical aptasensing   platform for highly sensitive detection of protein, Biosensors and   Bioelectronics, 2015, 66, 363–369.

12.    Jinfang Nie,   Yuanzhi Liang, Yun Zhang*, Shangwang Le, Dunnan Li and Songbai Zhang*,   One-step patterning of hollow microstructures in paper by laser cutting to   create microfluidic analytical devices, Analyst, 2013, 138: 671-676.

13.      Songbai Zhang, Zaisheng Wu*, Guoli   Shen*, and Ruqin Yu. Blank peak current-suppressed electrochemical   aptameric sensing platform for highly sensitive signal-on detection of small   molecule. Nucleic Acids Research, 2010, 38: e185.

14.      Songbai Zhang, ZaiSheng Wu*, Liping   Qiu, Hui Zhou, Guoli Shen* and Ruqin Yu. G-quadruplex signaling probe for   highly sensitive DNA detection. Chemical Communications, 2010, 46: 3381-3383.

15.      Songbai Zhang, Zaisheng Wu, Guoli   Shen*, and Ruqin Yu. A   label-free strategy for SNP detection with high fidelity and sensitivity   based on ligation-rolling circle amplification and intercalating of methyene   blue, Biosensors and Bioelectronics, 2009, 24: 3201-3207.

16.      Songbai Zhang, Fan Zheng, Zaisheng   Wu, Guoli Shen*, and Ruqin Yu.   Highly sensitive electrochemical detection of immunospecies based on   combination of Fc label and PPD film/gold nanoparticle amplification,   Biosensors and Bioelectronics, 2008, 24: 129-135.

17.    Songbai   Zhang, Zaisheng Wu, Mengmeng Guo, Guoli Shen* and Ruqin Yu. A novel   immunoassay strategy based on combination of chitosan and a gold nanoparticle   label, Talanta, 2007, 71: 1530-1535.